IMBRUVICA® (Ibrutinib) Is an Oral, Once-Daily Medication for Previously Treated Chronic Graft Versus Host Disease That Works Differently Than Steroids1
IMBRUVICA® works by blocking a protein in the blood, called Bruton’s tyrosine kinase, or BTK. By blocking BTK, IMBRUVICA® inhibits certain immune cells that play a role in cGVHD.
Because BTK is also found in some normal cells, blocking it may cause side effects.
Reference: 1. IMBRUVICA® (ibrutinib) Prescribing Information.