IMBRUVICA® oral suspension comes in a bottle
Taking IMBRUVICA® (ibrutinib)
How to take once-daily IMBRUVICA®
CLL/SLL: Adults
IMBRUVICA® is dosed once a day as either a single 420-mg tablet or three 140-mg capsules.
IMBRUVICA® tablets come in a blister pack
Take one 420-mg IMBRUVICA® tablet by mouth, at the same time each day with a glass of water.
Learn more about the IMBRUVICA® tablets blister pack
- It contains 28 tablets (a 4-week supply)
- Each tablet is identical
- Blister packs are available in different tablet strengths. Contact your doctor for dosing instructions
OR
IMBRUVICA® capsules come in a bottle
Take all three 140-mg IMBRUVICA® capsules by mouth, at the same time each day with a glass of water.
Learn more about the IMBRUVICA® capsules bottle
- The bottle contains a 30-day supply based on recommended dosing
- Each capsule is identical
Tablets and capsules are not shown at actual size. Talk to your doctor about which dosing option is right for you.
WM: Adults
IMBRUVICA® is dosed once a day as either a single 420-mg tablet or three 140-mg capsules.
IMBRUVICA® tablets come in a blister pack
Take one 420-mg IMBRUVICA® tablet by mouth, at the same time each day with a glass of water.
Learn more about the IMBRUVICA® tablets blister pack
- It contains 28 tablets (a 4-week supply)
- Each tablet is identical
- Blister packs are available in different tablet strengths. Contact your doctor for dosing instructions
OR
IMBRUVICA® capsules come in a bottle
Take all three 140-mg IMBRUVICA® capsules by mouth, at the same time each day with a glass of water.
Learn more about the IMBRUVICA® capsules bottle
- The bottle contains a 30-day supply based on recommended dosing
- Each capsule is identical
Tablets and capsules are not shown at actual size. Talk to your doctor about which dosing option is right for you.
Previously treated cGVHD: Adults
IMBRUVICA® is dosed once a day as either a single 420-mg tablet or three 140-mg capsules.
IMBRUVICA® tablets come in a blister pack
Take one 420-mg IMBRUVICA® tablet by mouth, at the same time each day with a glass of water.
Learn more about the IMBRUVICA® tablets blister pack
- It contains 28 tablets (a 4-week supply)
- Each tablet is identical
- Blister packs are available in different tablet strengths. Contact your doctor for dosing instructions
OR
IMBRUVICA® capsules come in a bottle
Take all three 140-mg IMBRUVICA® capsules by mouth, at the same time each day with a glass of water.
Learn more about the IMBRUVICA® capsules bottle
- The bottle contains a 30-day supply based on recommended dosing
- Each capsule is identical
Tablets and capsules are not shown at actual size. Talk to your doctor about which dosing option is right for you.
Previously treated cGVHD: Children (1 year and older)
For patients 12 years of age or older IMBRUVICA® is dosed once a day as either a single 420-mg tablet or three 140-mg capsules.
For patients 1 to less than 12 years of age talk to your doctor about dose options and the correct dose amount (based on the child's weight and height).
Helpful resources for preparing and dosing liquid IMBRUVICA®
Learn more about IMBRUVICA® Oral Suspension
- Glass bottle with child-resistant screw cap
- 2 reusable/washable oral dosing syringes
- Dose amount is dependent on the child's weight, height, and age
IMBRUVICA® tablets come in a blister pack
Take one 420-mg IMBRUVICA® tablet by mouth, at the same time each day with a glass of water.
Learn more about the IMBRUVICA® tablets blister pack
- It contains 28 tablets (a 4-week supply)
- Each tablet is identical
- Blister packs are available in different tablet strengths. Contact your doctor for dosing instructions
OR
IMBRUVICA® capsules come in a bottle
Take 140-mg IMBRUVICA® capsules by mouth, at the same time each day with a glass of water.
Learn more about the IMBRUVICA® capsules bottle
- The bottle contains a 30-day supply based on recommended dosing
- Each capsule is identical
Tablets and capsules are not shown at actual size. Talk to your doctor about which dosing option is right for you.
The most common side effects of IMBRUVICA® in adults with B-cell malignancies (CLL/SLL and WM) include: diarrhea, tiredness, muscle and bone pain, rash, bruising, and nausea.
The most common side effects of IMBRUVICA® in adults or children 1 year of age and older with cGVHD include: tiredness, low red blood cell count (anemia), bruising, diarrhea, low platelet count, muscle and joint pain, fever, muscle spasms, mouth sores (stomatitis), bleeding, nausea, stomach pain, pneumonia, and headache.
These are not all the possible side effects of IMBRUVICA®. Please read the full Important Side Effect Information to learn about these and other risks.
Also important to know:
- Take IMBRUVICA® exactly as your healthcare provider tells you to take it.
- Take IMBRUVICA® 1 time a day at about the same time each day.
IMBRUVICA® comes as capsules, tablets, and oral suspension.
- If your healthcare provider prescribes IMBRUVICA® capsules or tablets:
- Swallow IMBRUVICA® capsules or tablets whole with a glass of water.
- Do not open, break, or chew IMBRUVICA® capsules.
- Do not cut, crush, or chew IMBRUVICA® tablets.
- If your healthcare provider prescribes IMBRUVICA® oral suspension:
- See the detailed Instructions for Use that comes with IMBRUVICA® oral suspension for information about the correct way to give a dose to your child. If you have questions about how to give IMBRUVICA® oral suspension, talk to your healthcare provider.
- Do not use if the carton seal is broken or missing.
- If you miss a dose of IMBRUVICA® take it as soon as you remember on the same day. Take your next dose of IMBRUVICA® at your regular time on the next day. Do not take extra doses of IMBRUVICA® to make up for a missed dose.
- If you take too much IMBRUVICA®, call your healthcare provider or go to the nearest hospital emergency room right away.
Call your doctor or pharmacist if you have any questions.
While taking IMBRUVICA®
- Do not drink grapefruit juice
- Do not eat grapefruit
- Do not eat Seville oranges, often used in marmalade
These products may increase the amount of IMBRUVICA® in your blood.
Storing IMBRUVICA®
- Store IMBRUVICA® capsules and tablets at room temperature between 68°F and 77°F (20°C and 25°C)
- Keep IMBRUVICA® capsules in the original container with the lid tightly closed
- Keep IMBRUVICA® tablets in the original carton
- Store IMBRUVICA® oral suspension bottle between 36°F and 77°F (2°C and 25°C). Do not freeze
- Use IMBRUVICA® oral suspension within 60 days after opening the bottle. Throw away (discard) any unused portion 60 days after opening
Keep IMBRUVICA® and all medicines out of the sight and reach of children.
Tell your doctor about any other medications you are taking, including prescriptions or over-the-counter medications, vitamins, and herbal supplements. Taking IMBRUVICA® with certain other medicines may affect how IMBRUVICA® works and can cause side effects.
Some ways to stay on track with your treatment
It’s important to take your medicines exactly as directed by your doctor and creating a routine may help with your IMBRUVICA® treatment. Here are some ways to help you stay on course:
Link it. Take your medicine at the same time as something else you do on a daily basis, like walking the dog or brushing your teeth.
Hear it. Set a daily alarm on your phone, watch, or clock to go off when you need to take IMBRUVICA®.
See it. Use reminder notes or put your IMBRUVICA® container in a place you will see it (like next to your bed). Keep IMBRUVICA® out of the reach of children.
Use your tools. Use tools, such as an app on your smartphone, or a calendar, to set reminders for yourself.
Do not stop taking IMBRUVICA® without talking to your doctor. Always take IMBRUVICA® exactly as your doctor prescribes.
Reference: 1. IMBRUVICA® (ibrutinib) Prescribing Information.